Cmf therapy for breast cancer
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What is CMF chemotherapy? How does CMF work? When might CMF be prescribed? How is CMF given?
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Adjuvant chemotherapy in breast cancer: To use or not to use, the anthracyclines
CMF | Cancer information | Cancer Research UK
Clinical Trials: The NCCN recommends cancer patient participation in clinical trials as the gold standard for treatment. Cancer therapy selection, dosing, administration, and the management of related adverse events can be a complex process that should be handled by an experienced healthcare team. Clinicians must choose and verify treatment options based on the individual patient; drug dose modifications and supportive care interventions should be administered accordingly. The cancer treatment regimens below may include both U. These regimens are only provided to supplement the latest treatment strategies.
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Commonly used adjuvant systemic therapies harbor high rates of severe short-term and long-term side effects but are often justified to patients because of curative intent in early stage breast cancer. To address this misperception, we performed a review of all consecutive breast cancer patients at the Seattle Cancer Care Alliance over the past decade receiving 6 months of adjuvant CMF as their sole chemotherapy regimen and determined rates for relapse-free survival RFS , overall survival OS , and major organ toxicity. From January to August , patients median age of 52 years at the start of chemotherapy met criteria for inclusion in this series and had a median follow-up of 67 months. RFS and OS at 5 years was
The chemotherapy drug capecitabine gives patients a better quality of life and is as effective at preventing breast cancer from returning as the alternative regimen called CMF, when given following epirubicin. Around 4, patients on the TACT2 clinical trial were treated with the chemotherapy drug epirubicin followed by either capecitabine or CMF, after surgery. Researchers at The Institute of Cancer Research, London, and the Cancer Research UK Edinburgh Centre found that capecitabine resulted in patients experiencing fewer side effects and having a better quality of life, and it was as effective at preventing cancer's return as CMF. Most patients experienced some side effects regardless of the treatment they were given.
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